The Causes of IBS

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The Latest Published Research

Uz, et. al.(2007). Risk factors for irritable bowel syndrome in Turkish population: role of food allergy. J Clin Gastroenterol. 2007 Apr;41(4):380-3. Abstract Only

Cranney, et. al.(2007). The Canadian Celiac Health Survey. Dig Dis Sci. 2007 Apr;52(4):1087-95. Epub 2007 Feb 22

Grazioli, Barbara et. al.(2006). Giardia lamblia infection in patients with irritable bowel syndrome and dyspepsia: A prospective study. World Journal of Gastroenterology, World J Gastroenterol 2006 March 28; 12(12): 1941-1944

Wood, J.D. (2006). Histamine, mast cells, and the enteric nervous system in the irritable bowel syndrome, enteritis,and food allergies. Gut 2006;55;445-447

Khan, W.I. and S.J. Collins (2006). Gut motor function: immunological control in enteric infection and inflammation. Clinical and Experimental Immunology 2006; 143:389–397

Zar, Sameer; Martin J. Benson; and Devinder Kumar (2005). Food-Specific Serum IgG4 and IgE Titers to Common Food Antigens in Irritable Bowel Syndrome. American Journal of Gastroenterology 2005; 100:1550-1557

Yamaguchi N., Sugita R., Miki A., Takemura N., Kawabata J., Watanabe J.,and Sonoyama K. (2006). Gastrointestinal Candida colonisation promotes sensitisation against food antigens by affecting the mucosal barrier in mice. Gut 2006;55:954-960

Whorwell, P.J. et. al. (2006). Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. American Journal of Gastroenterology 2006 Jul;101(7):1581-90. (abstract only)

References

Amadi, B. (2002). Role of food antigen elimination in treating children with persistent diarrhea and malnutrition in Zambia. Journal of Pediatric Gastroenterology and Nutrition, 34(Suppl. 1), S54-S56.

Armentia, A., Rodriguez, R., Callejo, A., Martin-Esteban, M., Martin-Santos, J. M., Salcedo, G., Pascual, C., Sanchez-Monge, R., & Pardo, M. (2002). Allergy after ingestion or inhalation of cereals involves similar allergens in different ages. Clinical and Experimental Allergy, 32(8), 1216-1222.

Avonts, L., & De Vuyst, L. (2001). Antimicrobial potential of probiotic lactic acid bacteria. Meded Rijksuniv Gent Fak Landbouwkd Toegep Biol Wet, 66(3b), 543-550.

Brown, S., Kerrigan, P., & Waterston, T. (2000). A six-year old suffering from constipation. Practitioner, 244(1607), 63-68

Carroccio, A., Montalto, G., Custro, N., Notarbartolo, A., Cavataio, F., D'Amico, D., Alabrese, D., & Iacono, G. (2000). Evidence of very delayed clinical reactions to cow's milk in cow's milk-intolerant patients. Allergy, 55(6), 574-579.

Cavataio, F., Carroccio, A., & Iacono, G. (2000). Milk-induced reflux in infants less than one year of age. Journal of Pediatric Gastroenterology and Nutrition, 30(Suppl.), S36-S44.

Chin, K. C., Tarlow, M. J., & Allfree, A. J. (1983). Allergy to cows' milk presenting as chronic constipation. British Medical Journal (Clinical Research Edition), 287(6405), 1593.

Cremonini, F., Di Caro, S., Santarelli, L., Gabrielli, M., Candelli, M., Nista, E. C., Lupascu, A., Gasbarrini, G., & Gasbarrini, A. Probiotics in antibiotic-associated diarrhoea. Digestive and Liver Disease, 34(Suppl. 2), S78-S80.

Daher, S., Tahan, S., Sole, D., Naspitz, C. K., Da Silva Patricio, F. R., Neto, U. F., & De Morais, M. B. (2001). Cow's milk protein intolerance and chronic constipation in children. Pediatric Allergy and Immunology, 12(6), 339-342.

de Boissieu, D., & Dupont, C. (2000). Infant food allergy: Digestive manifestations [Article in French]. Allergie et Immunologie, 32(10), 378-380.

Delgado, S., Florez, A. B., & Mayo, B. (2005). Antibiotic susceptibility of Lactobacillus and Bifidobacterium species from the human gastrointestinal tract. Current Microbiology, 50(4), 202-207.

Elmer, G. W. (2001). Probiotics: "Living drugs." American Journal of Health-System Pharmacy, 58(12), 1101-1109.

Floch, M. H., & Narayan, R. (2002). Diet in the irritable bowel syndrome. Journal of Clinical Gastroenterology, 35(1, Suppl.), S45-S52.

Foster, A. P., Knowles, T. G., Moore, A. H., Cousins, P. D., Day, M. J., & Hall, E. J. (2003). Serum IgE and IgG responses to food antigens in normal and atopic dogs, and dogs with gastrointestinal disease. Veterinary Immunology and Immunopathology, 93(3-4), 113-124.

Fox, C. H., & Dang, G. (2004). Probiotics in the prevention and treatment of diarrhea. Journal of Alternative and Complementary Medicine, 10(4), 601-603.

Goldin, B. R. (1998). Health benefits of probiotics. British Journal of Nutrition, 80(4), S203-S207.

Guarner, F. & Malagelada, J. R. (2003). Gut flora in health and disease.. Lancet, 361(9356), 512-519.

Heine, R. G., Elsayed, S., Hosking, C. S., Hill, D. J. (2002). Cow's milk allergy in infancy. Current Opinion in Allergy and Clinical Immunology, 2(3), 217-225.

Iacono, G., Carroccio, A., Cavataio, F., Montalto, G., Cantarero, M. D., & Notarbartolo, A. (1995). Chronic constipation as a symptom of cow milk allergy. Journal of Pediatrics, 126(1), 34-39.

Iacono, G., Cavataio, F., Montalto, G., Florena, A., Tumminello, M., Soresi, M., Notarbartolo, A., & Carroccio, A. (1998). Intolerance of cow's milk and chronic constipation in children. New England Journal of Medicine, 229(16), 1100-1104.

Iacono, G., Cavataio, F., Montalto, G., Soresi, M., Notarbartolo, A., & Carroccio, A. (1998). Persistent cow's milk protein intolerance in infants: the changing faces of the same disease. Clinical and Experimental Allergy, 28(7), 817-823.

Ishida, Y., Nakamura, F., Kanzato, H., Sawada, D., Hirata, H., Nishimura, A., Kajimoto, O., & Fujiwara, S. (2005). Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: A double-blind, placebo-controlled study. Journal of Dairy Science, 88(2), 527-533.

Jirapinyo, P., Densupsoontorn, N., Thamonsiri, N., & Wongarn, R. (2002). Prevention of antibiotic-associated diarrhea in infants by probiotics. Journal of the Medical Associatioin of Thailand, 85(Suppl. 2), S739-S742.

Klein, K. B. (1988). Controlled treatment trials in the irritable bowel syndrome: A critique. Gastroenterology, 95, 232-241.

Kokkonen, J., Ruuska, T., Karttunen, T. J., & Niinimaki, A. (2001). Mucosal pathology of the foregut associated with food allergy and recurrent abdominal pains in children. Acta Paediatrica, 90(1), 16-21.

Latcham, F., Merino, F., Lang, A., Garvey, J., Thomson, M.A., Walker-Smith, J. A., Davies, S. E., Phillips, A. D., & Murch, S. H. (2003). A consistent pattern of minor immunodeficiency and subtle enteropathy in children with multiple food allergy. Journal of Pediatrics, 143(1), 39-47.

Lee, M. C., Lin, L. H., Hung, K. L., & Wu, H. Y. (2001). Oral bacterial therapy promotes recovery from acute diarrhea in children. Acta Paediatrica Taiwanica, 42(5), 301-305.

Lembo, A. (2004 Irritable bowel syndrome medications side effects survey. Journal of Clinical Gastroenterology, 38(9), 776-781

McGrath, J. (1984). Allergy to cow's milk presenting as chronic constipation. British Medical Journal (Clinical Research Edition), 288(6412), 236.

Magazzu, G., & Scoglio, R. (2002). Gastrointestinal manifestations of cow's milk allergy. Annals of Allergy, Asthma, & Immunology, 89(6, Suppl. 1), 65-68.

Matto J, Maunuksela L, Kajander K, Palva A, Korpela R, Kassinen A, Saarela M. (2005). Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome--a longitudinal study in IBS and control subjects. FEMS Immunology and Medical Microbiology, 2005 Feb 1;43(2):213-22.

Moon, A., & Kleinman, R. E. (1995). Allergic gastroenteropathy in children. Annals of Allergy, Asthma, & Immunology, 74(1), 5-12.

Mora, W. (2003). Cow's milk protein intolerance and childhood constipation. American Family Physician, 68(6), 1016.

Nadasdi, M. (1992). Tolerance of a soy formula by infants and children. Clinical Therapeutics, 14(2), 236-241.

Orenstein, S. R., Shalaby, T. M., Di Lorenzo, C., Putnam, P. E., Sigurdsson, L., Mousa, H., & Kocoshis, S. A. (2000). The spectrum of pediatric eosinophilic esophagitis beyond infancy: A clinical series of 30 children. American Journal of Gastroenterology, 95(6), 1422-1430.

Parry S, Forgacs I. (2005). Intestinal infection and irritable bowel syndrome. Eur J Gastroenterol Hepatol. 2005 Jan;17(1):5-9. Abstract

Pelto, L., Impivaara, O., Salminen, S., Poussa, T., Seppanen, R., & Lilius, E. M. (1999). Milk hypersensitivity in young adults. European Journal of Clinical Nutrition, 53(8), 620-624.

Petitpierre M, Gumowski P, Girard JP. (1985). Irritable bowel syndrome and hypersensitivity to food. Annals of Allergy, 1985 Jun;54(6):538-40.

Rastall, R. A. (2004). Bacteria in the gut: Friends and foes and how to alter the balance. Journal of Nutrition, 134(8, Suppl.), S2022-S2026.

Romanczuk, W., & Samojedny, A. (2003). The assessment of the influence of IgE-mediated food allergy on colonic transit time in children with chronic constipation [Article in Polish]. Pol Merkuriusz Lek, 15(87), 226-230.

Saalman, R., Dahlgren, U. I., Fallstrom, S. P., Hanson, L. A., Ahlstedt, S., & Wold, A. E. (2003). Avidity progression of dietary antibodies in healthy and coeliac children. Clinical and Experimental Immunology, 134(2), 328-334.

Santelmann, Heiko a; Howard, John McLaren b (2005). Yeast metabolic products, yeast antigens and yeasts as possible triggers for irritable bowel syndrome. European Journal of Gastroenterology & Hepatology. 17(1):21-26, January 2005. Abstract

Sabra, A., Bellanti, J. A., Rais, J. M., Castro, H. J., de Inocencio, J. M., & Sabra, S. (2003). IgE and non-IgE food allergy. Annals of Allergy, Asthma, & Immunology, 90(6, Suppl. 3), 71-76.

Saggioro, A. (2004). Probiotics in the treatment of irritable bowel syndrome. Journal of Clinical Gastroenterology, 38(6, Suppl.), S104-S106.

Salvatore, S., & Vandenplas, Y. (2002). Gastroesophageal reflux and cow milk allergy: Is there a link? Pediatrics, 110(5), 972-984.

Shah, N., Lindley, K., & Milla, P. (1999). Cow's milk and chronic constipation in children. New England Journal of Medicine, 340(11), 891-892.

Sicherer, S. H. (2003). Clinical aspects of gastrointestinal food allergy in childhood. Pediatrics, 111(6, Pt. 3), 1609-1616

Simadibrata M, Tytgat GN, Yuwono V, Daldiyono, Lesmana LA, Syam AF, Ariawan I, Rani A.(2004), Microorganisms and parasites in chronic infective diarrhea. Acta Medica Indonesiana, 2004 Oct-Dec;36(4):211-4.

Speer, F. (1975). The allergic child. American Family Physician, 11(2), 88-94.

Stricker, T., & Braegger, C. P. (2000). Constipation and intolerance to cow's milk. Journal of Pediatrics Gastroenterology and Nutrition, 30(2), 224.

Strobel, S,, & Hourihane, J. O. (2001). Gastrointestinal allergy: Clinical symptoms and immunological mechanisms. Pediatric Allergy and Immunology, 12(Suppl. 14), 43-46.

Taylor, C. J., Hendrickse, R. G., McGaw, J., & Macfarlane, S. B. (1988). Detection of cow's milk protein intolerance by an enzyme-linked immunosorbent assay. Acta Paediatrica Scandinaica, 77(1), 49-54.

Vanderhoof, J. A, Perry, D., Hanner, T. L, & Young, R. J. (2001). Allergic constipation: association with infantile milk allergy. Clinical Pediatrics, 40(7), 399-402.

Vanderhoof, J. A., & Young, R. J. (2001). Allergic disorders of the gastrointestinal tract. Current Opinion in Clinical Nutriton and Metabolic Care, 4(6), 553-556.

Walter SA, Skagerstrom E, Bodemar G. (2004). Subgroups of irritable bowel syndrome: a new approach. Eur J Gastroenterol Hepatol. 2004 Oct;16(10):991-4. Abstract

Wynne AG, McCartney AL, Brostoff J, Hudspith BN, Gibson GR. (2004). An in vitro assessment of the effects of broad-spectrum antibiotics on the human gut microflora and concomitant isolation of a Lactobacillus plantarum with anti-Candida activities. Anaerobe. 2004 Jun;10(3):165-9. Abstract

Yimyaem, P., Chongsrisawat, V., Vivatvakin, B., & Wisedopas, N. (2003). Gastrointestinal manifestations of cow's milk protein allergy during the first year of life. Journal of the Medical Association of Thailand, 86(2), 116-123.

Zoppi, G. (1996). The most common gastrointestinal problems in pediatric practice [Article in Italian]. Pediatria Medica e Chirurgica, 18(2), 131-139.